Optical bio-imaging lab
Publications
CMS
Pre-Prints
R.Chadha‡, A. Colazo‡, J. Ambarian, Z. Yang, P. Kocheril, B. Yang, and L. Wei*. bioRxiv. 2026.
‡ denotes equal contribution
R.Chadha‡, P. Kocheril‡, A. Colazo‡, E. Kapelczak, B. Suen, Z. Yang, T. TeSlaa, and L. Wei*. bioRxiv. 2026.
‡ denotes equal contribution
X. Liu*, D.Yuan, Y. Luo, X. Tang, A. Tapia, N. Malhi, R. Chadha, S. Tiwari, P. Swiderski, K-C. Wang, M. Kortylewski, N. Pardi, L. Wei, W. Huang, Z. Chen*. bioRxiv. 2025.
L-E. Lin, X. Bi, A. Colazo, H. Wang, and L. Wei*. Chemical & Biomedical Imaging. 2026.
P. Kocheril, R. Leighton, N. Naji, D. Lee, H. Wang, J. Du, and L. Wei*. Journal of Chemical Physics. 2026, 164, 130901.
P. Kocheril, H. Wang, R. Leighton, D. Lee, N. Naji, W. Min, and L. Wei*. Chemical Science. 2026, 17, 5297-5316.
N. Malhi, Y. Luo, M. Chen, X. Tang, D. Yuan, R. Chadha, A. Tapia, S. Yin, X. Liu, M. Qi, M. Reddy, J. Sun, J. Otto, L. Wei, J. P. Cooke, E. Lee, R. Natarajan, K.W. Southerland, Z.B. Chen*. Science Translational Medicine. 2026. 18, 846.
X. Bi, B. Suen, L-E. Lin, K. Miao, L. Wei*. Proceedings of the National Academy of Sciences. 2026, 123, 4, e2505321123.
R. Chadha, B. Yang, D. Yuan, E. Kapelczak, P. Kocheril, A. Tapia, S. Mahajan, A.Colazo, N. Malhi, J. Ambarian, X. Liu, T. TeSlaa, Z. Chen*, L. Wei*. Advanced Science. 2025, 13, 7, e08517 (*Co-corresponding)
P. Kocheril, D. Lee, N. Naji, R. Chadha, R. Leighton, H. Wang, and L. Wei*. Journal of Physical Chemistry B. 2025, 129, 34, 8788–8797.
P. Kocheril, J. Du, H. Wang, R. Leighton, D. Lee, Z. Yang, N. Naji, A. Colazo, and L. Wei*. Chemical Science. 2025, 16, 14905-14918.
This article is part of the themed collections: 2025 Chemical Science Covers and Most popular 2025 sensing & imaging articles
A. Colazo, K. Miao, L-E. Lin, R. Chadha, C. Qian, X. Bi, P. Kocheril, L. Wei*,
Biomedical Optics Express. 2025.16, 2430-2439
N. Qian, Z. Zhao, E. Khoury, X. Gao, C. Canela, Y. Shen, L. Shi, L. Shi, F. Hu,
L. Wei, Wei Min*. Nature Methods, 2025, 22, 928–944.
N. Qian*, H. Xiong*, L. Wei*, L. Shi*, and Wei Min*. Annual Review of Physical Chemistry, 2025, 76, 279-301. (*Co-corresponding)
L. Lin, A. Colazo, X. Bi, J. Du, L. Wei.* Small Methods. 2025, 10, 2, 2500382.
D. Lee, H. Wang, P. Kocheril, X. Bi, N. Naji, L. Wei*, Optica. 2025, 12 (2), 148–157.
H. Wang, P. Kocheril, Z. Yang, D. Lee, N. Naji, J. Du, L. Lin, L. Wei.* Angewandte Chemie. 2024, 63 (52), e202413647.
P. Kocheril, H. Wang, D. Lee, N. Naji, and L. Wei.* Journal of Physical Chemistry Letters. 2024, 15, 19, 5306–5314.
C. Qian†, H. Liu†, P. Chittur, R. Chadha, Y. Yao, J. Kornfield, D. Tirrell*, and L. Wei.* Analytical Chemistry. 2024, 96, 17, 6540–6549. (†Equal contributions, *Co-corresponding)
R. Chadha†, J.Guerrero†, L. Wei*, L. Sanchez.* ACS Central Science. 2024, 10 (4), 758-774. (†Equal Contributions; *Co-corresponding)
**Supplementary Cover
H. Wang†, D. Lee†, Y. Cao, X. Bi, J. Du, K. Miao & L. Wei*, Nature Photonics. 2023, 17, 846–855. (†Equal Contributions)
"BonFIRE Ignites a New Era in Microscopy: Unveiling the Molecular Diversity of Life in Stunning Detail”, featured by SciTechDaily.
"Microscopy Method Uses Infrared Light to Image Molecules with Vibrational Contrast”, featured by Photonics Spectra.
"New Combination of Imaging Techniques Could Revolutionize Microscopy”, featured by Technology Networks.
34. Computational Design of Molecular Probes for Electronic Preresonance Raman Scattering Microscopy
J. Du†, X. Tao†, T. Begušić*, & L. Wei*, Journal of Physical Chemistry B. 2023, 127 (22), 4979-4988.
(†Equal Contributions, *Co-corresponding)
H. Wang, D. Lee, & L. Wei*, Chemical & Biomedical Imaging. 2023, 1 (1), 3-17.
J. Du, H. Wang & L. Wei*, ACS Chemical Biology 2022, 17 (7), 1621-1637.
**Supplementary Cover
K. Miao, L. Lin, C. Qian & L. Wei*, Journal of Visualized Experiments. 2022, 183, e63824.
X. Bi†, K. Miao† & L. Wei*, Journal of the American Chemical Society. 2022. 144 (19), 8504-8514.
†Equal Contributions
J. Du & L. Wei*, Journal of the American Chemical Society. 2022. 144 (2), 777-786.
**Supplementary Cover
C. Qian†, K. Miao†, L. Lin, X. Chen, J. Du, L. Wei*, Nature Communications. 2021, 3648. †Equal Contributions
“Microscopy method achieves superresolution without labels”,
featured by C&EN.
"C&EN’s Year in Chemistry 2021"
L. Lin, K. Miao, C. Qian, L. Wei*, Analyst. 2021, 146, 4135-4145.
**Supplementary Cover
D. Lee, C. Qian, H. Wang, L. Lei, K. Miao, J. Du, D. M. Shcherbakova, V. V. Verkhusha, L.V. Wang, and L. Wei*, Journal of Chemical Physics. 2021.154, 135102.
- As a part of the 2021 JCP Emerging Investigators Special Collection
- JCP Editors’ Choice 2021
- Featured article
D. Lee, J. Du, R. Yu, Y. Su, J. Heath, and L. Wei*, Analytical Chemistry. 2020. 92, 13182.
J. Du†, Y. Su†, C. Qian, D. Yuan, K. Miao, D. Lee, A. Ng, R. Wijker, A. Ribas, R. Levine, J. Heath*, and L. Wei*, Nature Communications. 2020. 11, 4830.
†Equal Contributions
"Cancer’s Hidden Vulnerabilities” featured by ScienMag.
"Metabolic Processes in Cancer Cells Studied via Pharmaco-Metabolomics Approach” featured by Genetic Engineering & Biotechnology News.
“Exposing Cancer's Vulnerabilities Using Specialized Microscopy” featured by Technology Networks.
K. Miao and L. Wei*, ACS Central Science. 2020, 4, 478.
M. Wei†, L. Shi†, Y. Shen, Z. Zhao, A. Guzman, L. J. Kaufman, L. Wei* and Wei Min*, Proceedings of the National Academy of Sciences. 2019. USA, 116, 6608. (†Equal Contributions *Co-corresponding)
H. Xiong†, L. Shi†, L. Wei, Y. Shen, R. Long, Z. Zhao and W. Min*, Nature Photonics, 2019. 13, 412.
†Equal Contributions
Peer-Reviewed Publications
H. Wang, J. Du, D. Lee, and L. Wei. Stimulated Raman Scattering Microscopy, Techniques and Applications, 2022, Pages 289-310
Prior to Caltech:
20. Electronic Resonant Stimulated Raman Scattering Micro-Spectroscopy
H. Xiong†, L. Shi†, L. Wei, Y. Shen, R. Long, Z. Zhao and W. Min, Nat. Photonics, 13, 412 (2019). †Equal Contributions
L. Wei and W. Min, J. Phys. Chem. Lett. 9, 4294 (2018). Cover.
Q. Cheng†, L. Wei†, Z. Liu, N. Ni, Z. Sang, B. Zhu, W. Xu, L.-Q.Chen, W. Min and Y. Yang, Nat. Commun., 9, 2942 (2018). †Equal contribution.
F. Hu, C. Zeng, R. Long, Y. Miao, L. Wei, Q. Xu and W. Min, Nat. Methods, 15, 194(2018).
L. Wei, Z. Chen, L. Shi, R. Long, A. V. Anzalone, L. Zhang, F. Hu, R. Yuste, V. W. Cornish and W. Min, Nature, 544, 465 (2017).
“A larger palette for biological imaging” featured by Nature News & Views.
“New dyes enable super-multicolor imaging”, featured by Chem & Engn News.
“Good vibrations for super-multiplexed imaging” featured by Nature Methods.
“New microscopy method breaks color barrier of optical imaging” featured by Phys.org.
“Expanding Bioimaging's Palette” featured by Optics & Photonics News.
L. Wei, F. Hu, Z. Chen, Y. Shen, L. Zhang and W. Min, Acc. Chem. Res.,49,1494 (2016).
F. Hu, M. Lamprecht, L. Wei, B. Morrison and W. Min, Sci. Rep.,6, 39660 (2016).
L. Wei, Y. Shen, F. Xu, F. Hu, J. K. Harrington, K. L. Targoff and W. Min. ACS Chem. Bio.10, 901 (2015). Cover.
F. Hu, Z. Chen, L. Zhang, Y. Shen, L. Wei and W. Min. Angew. Chem. Int. Ed. 54, 9821 (2015).
L. Wei, F. Hu, Y. Shen, Z. Chen, Y. Yu, C. -C. Lin, M. C. Wang and W. Min. Nat. Methods, 11, 410 (2014).
Z. Chen, D. Paley, L. Wei, A. Weisman, R. Friesner, C. Nuckolls and W. Min. J. Am. Chem. Soc. 136, 8027 (2014).
Y. Shen, F Xu, L. Wei, F. Hu and W. Min, Angew. Chem. Int. Ed.53, 5596 (2014).
F. Hu, L. Wei, C. Zheng, Y. Shen and W. Min, Analyst, 139, 2312 (2014). Cover.
L. Wei, Y. Yu, Y. Shen, M. Wang and W. Min, Proc. Natl. Acad. Sci. USA,110, 11226 (2013).
F. Xu, L. Wei, Z. Chen and W. Min. Opt. Express, 12, 14097 (2013).
L. Wei and W. Min. Ann. N. Y. Acad. Sci., 1293,1 (2013).
L. Wei and W. Min. Anal. Bioanal. Chem.403, 2197 (2012).
E. Gatzogiannis, Z. Chen, L. Wei, R. Wombacher, Y. -T. Kao, G. Yefremov, V. C. Cornish and W. Min. Chem. Commun. 48, 8694 (2012).
Z. Chen†, L. Wei†, X. Zhu† and W. Min. Opt. Express 20, 18525 (2012). †Equal contribution
L. Wei, Z. Chen and W. Min. Biomed. Opt. Express 3, 1465 (2012).
